I am not sure about the RF extender hopefully someone else will chime in on that one. RF is set per device so you couldn't have RF and IR on the same device but there is nothing that says you couldn't have 2 hidden devices (one with RF commands, one with IR commands) with a third device which has buttons that link to functions on the either the RF or IR device. So easy answe is yes you can have a mix or IR and RF devices.

The NG software is NOT limited to one page per device.

Cooch