1) The Pronto cannot talk RF directly to Bose. What Bose equipment do you have? if it is one of those that can also do IR, then the Pronto needs to talk to the RF base and then the RF base will talk to the Bose. If it is not, then you also need an other device that talks Bose RF.

2) a Macro can do some RF commands and some IR, but what it will sends depends on where the actual command is located.