Here is what I have:

Mitsubishi 46809
Panasonic E80
Denon 2803 AV Surround Receiver
Motorola DCT6200

I've tried the Sony AV3000, Harmony 880 and that's the
ones worth mentioning.

I don't remember what I didn't like about the Sony, but
I definately know I never liked being stuck with the button
labels and layout on the screen.

On the Harmony I had a couple problems with. how it worked.
First, it didn't sit in the cradle well enough that it
would not charge. No big deal except that if it worked
how I really wanted it would still be annoying. The main
issue I think I had (it's been awile since I used it)
was that it tried to keep track of whether the power was
on or off. In addition, I belive it was too slow when
trying to do commands with multiple devices.

I guess what I am looking for is a remote I can tell it
to turn on the TV, the AMP, the DVD player, change the
amp to DVD input then wait 10 seconds to put the TV on
the DVD input.

I'm looking at several remotes like the URC MX-950, Nevo
and RTI remotes.

Basically I need a remote that I can setup that really
works that if I was gone for a week I would not have to
worry about it p*ssing my wife off.