I can only assume that those that give up and return a Harmony "because it didn't work" were either too lazy or not bright enough to set it up properly. That is the only downfall - you can't expect some joe blow or an elderly person to set one of these things up. You do have to be slightly technical and take the time to get used to the (somewhat poorly laid out I will admit) software.

Once set up, the remotes are trouble free for the most part.