All Harmony remotes use the same database so if it can or cannot be done on one remote, it will be the same for all other Harmony remotes. Do you use an IR543 X10 receiver? If so is it added to your Activity. You can add additional commands when you start and leave an activity. Re-Run the Setup for that activity at the end select yes but I want to add more control, you will have to re-run the setup again , but ad the end you can add additional commands to either the start or the end of the activity. For the end of the Activity select your IR543 and add the additional commands to turn off your X10 module first command will be the Unit number of your module, and the next command will be the off command. Then update your remote