Yes, Ernie. I find some live events fatiguing. But usually there is a direct correlation to distance.

Strings are tiring, so are certain other instruments. Can't really come up with a list offhand, haven't thought about it in a long while.

None of these is as bad as CD, however.

G50, this isn't my muscles getting tired. It is weariness brought on by the sound. And it is less bad with more skill of the artist, but scraping strings is painful to the ears in certain conditions no matter what. Back off a couple steps and that goes away, IME. I simply wouldn't be able to play violin much, too high pitched for my ears at a couple inch range.

BTW, (and no doubt this will shock you) different people have different tolerancies for their senses. How much heat on their hand, how loud sound of various types can be played, etc. If it doesn't bother you as much, great.