Price no object: Probably a Pronto. It seems to the best configurability to get your setup exactly the way you want it. I like the fact that you can share your codes and with the PC software, there is no end to the setups you can have. I'd still miss the real buttons of the Marantz though. The Take Control is too clunky for me though. From this site and many other sites, it SEEMs as though there are a larger percentage of unhappy Take Control users than others.

I'd rank them Pronto, RC2000, Take Control if price no object. Of course, there are much more expensive ones but they are not easily hand held.