I just bought a "Big Button" remote made by Hy-Tek Manufacturing - www.hytekmfg.com - for my 82 year old father who has pretty severe macular degeneration. So far, it seems to be working quite well for him. Only problem I have is trying to track down a code to program it to operate a Samsung DVD/VCR combo deck I bought for him. Sells for $25. I found it at Brookstone.