In a home theater where we had a 35' RG59 and a 16/4 ran between a surround receiver and a powered sub...

The RG59 was causing a crazy hum in the sub. The 16/2 was ran JIC we went with a passive sub. Out of desperation i soldered an RCA male at each end of the 16/2 and it worked just fine.

Whatever caused the hum with the RG59 wasn't bothering the 16/2. I don't remember what the RG59 was but we used it often for line level audio back then. Never had any issues with it until that subwoofer.