In the DIY space, nothing that I'm aware of.

Pads and phones are so ubiquitous that no company can generate enough economy of scale to justify manufacturing the hardware. "Can't I just use my pad or phone" is the common refrain. We can spout the benefits of hard buttons and dedicated remotes, however, "but, I always have my phone with me," is the retort.

There is Harmony, but former Pronto users don't think that Harmony is "customizable" at the required level.

If you can live with iPad/iPhone, TouchControl is very configurable.