The TouchSquid tablet makes a great replacement for a Pronto. I have had mine for a while now, and in addition to a very good remote app, it handles web surfing and email.
I can even watch Netflix right on the razor-sharp 7" LCD screen.
The price is lower than any Pronto, even most used ones. They are available at RemoteShoppe and SimpleRemoteControl, maybe a few other places.
The developers are very responsive and have added features requested by several users. IconHarmony.com is opening up a TouchSquid section which will eventually offer a huge selection of TS compatible icons.
The TouchSquid is still new, and the software has been evolving rapidly. One of the big advantages over a Pronto or Harmony is the ability to same multiple room profiles. This makes the TouchSquid portable between rooms.
With Wifi and Bluetooth it is also an excellent small computer. I don't play games, but apparently they work well and there is a huge selection available.
I do watch YouTube on it sometimes -- only cute dog vidoes of course!