Your choices in do-it-yourself advanced $300-$500 remotes is getting very slim. Either a now-discontinued Pronto (likely TSU9300), or something from the URC family (bought from somewhere who will for sure give you the software).

I think some more on what you're looking for will help. Touchscreen? Hard buttons? Rechargeable? Do you want an RF basestation (so you don't have to point and can use it from other rooms)? And so forth...